Upgraded Version Recombinant Human Growth Differentiation Factor 5/bone Morphogenetic Protein-14 (human Gdf-5/bmp-14)_c230359 Bonkers Deal: 30% Off [6Hq0uEpD]

Introducing Recombinant Human Growth Differentiation Factor 5/Bone Morphogenetic Protein-14 (Human GDF-5/BMP-14)

The Recombinant Human Growth Differentiation Factor 5/Bone Morphogenetic Protein-14 (Human GDF-5/BMP-14) is a highly purified, biologically active protein that is ideal for research applications. Derived from E. coli and designed to mimic the native human GDF-5/BMP-14, this protein is a powerful tool for studying cell signaling, differentiation, and morphogenesis. Its exceptional purity, as confirmed by >95% by SDS-PAGE and HPLC analyses, ensures reliable and consistent results in your experiments.

Product Features and Specifications

Our Human GDF-5/BMP-14 is expressed as a homodimeric precursor protein with a molecular weight of approximately 27.1 kDa. It consists of a 354 amino acid N-terminal pro-region and a 120 aa C-terminal mature peptide, providing the complete structure necessary for its biological activity. This recombinant protein shares 99% amino acid sequence identity with mature mouse and rat GDF-5, ensuring cross-species compatibility. The product is available as a sterile, filtered white lyophilized powder, ready for immediate use. Its formulation includes a 0.2 µm filtered solution in 30% Acetonitrile and 0.1% TFA, ensuring optimal solubility and stability.

Applications and Benefits

Human GDF-5/BMP-14 is a crucial player in various developmental processes, including limb generation, cartilage development, joint formation, bone morphogenesis, cell survival, and neuritogenesis. This makes it an invaluable resource for researchers studying these areas. The product boasts high biological activity, as evidenced by its ED50 value, which is less than 1.0 μg/mL when measured by inducing alkaline phosphatase production in murine ATDC5 cells. Additionally, it is endotoxin-free, with <0.1 EU per 1 μg of the protein as determined by the LAL method. These features make Human GDF-5/BMP-14 the perfect choice for your research needs, providing you with the highest quality and reliability.