Hot Sale Pureselect Protein G-agarose Fast-flow Pro Version [V1M86icR]

Hot Sale Pureselect Protein G-agarose Fast-flow Pro Version [V1M86icR]: Advanced Immunoglobulin Purification

Introducing the Hot Sale Pureselect Protein G-agarose Fast-flow Pro Version [V1M86icR], a cutting-edge affinity chromatography medium designed to simplify and enhance the purification process of immunoglobulins. This high-quality resin is specifically engineered for efficient, one-step purification of classes, subclasses, and fragments of immunoglobulins from biological fluids and cell culture media. With its superior binding capacity and specific binding characteristics, Hot Sale Pureselect Protein G-agarose Fast-flow Pro Version [V1M86icR] is a reliable choice for researchers and scientists in various fields.

Key Product Features and Specifications

The Hot Sale Pureselect Protein G-agarose Fast-flow Pro Version [V1M86icR] is crafted with a recombinant protein G ligand coupled to 4% highly cross-linked agarose. This combination offers a static binding capacity of over 20 mg sheep IgG/ml settled resin, ensuring efficient purification. The dynamic binding capacity may vary based on factors like target antibody and flow rate. Protein G, derived from group G Streptococci, binds to mammalian IgGs primarily through the Fc region, making it ideal for isolating mammalian monoclonal and polyclonal IgGs that do not bind well to protein A. The native protein G has three IgG binding domains, as well as sites for albumin and cell surface binding, which have been eliminated in the recombinant form to minimize nonspecific binding.

Practical Applications and Target Audience

The Hot Sale Pureselect Protein G-agarose Fast-flow Pro Version [V1M86icR] is a versatile tool for researchers in immunology, biochemistry, and molecular biology. It is particularly beneficial for isolating mammalian IgGs, including human IgG3, mouse IgG1, and rat IgG2a, from various sources. Its superior affinity for mammalian IgGs, especially certain subclasses, and lack of binding to human IgM, IgD, and IgA, make it a preferred choice for those looking to purify specific immunoglobulin fractions. With its ease of use and high purity, Hot Sale Pureselect Protein G-agarose Fast-flow Pro Version [V1M86icR] is an indispensable resource for scientists seeking reliable and efficient purification solutions.