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MG-132: The Ultimate Proteasome Inhibitor

MG-132 is a cutting-edge reversible proteasome inhibitor that stands out in its class due to its exceptional purity of >98%. This powerful peptide aldehyde is designed to effectively block proteasome activities in mammalian cells, making it an invaluable tool in various research applications. Its cell permeability ensures that it can be easily used across a wide range of cell types, providing consistent and reliable results.

Key Product Features

High Purity: MG-132 is available at an impressive >98% purity, ensuring the highest quality and reliability for your experiments.

• Reversible Inhibition: Its reversible nature allows for the reversal of proteasome inhibition, making it suitable for various research applications.
• Cell Permeable: MG-132 is cell permeable, allowing for easy application across a wide range of cell types.

Applications and Benefits

MG-132 is a versatile tool for researchers seeking to investigate the role of proteasome activity in various cellular processes. Its ability to induce apoptotic cell death through the formation of reactive oxygen species (ROS) makes it particularly useful in studies of cell viability and apoptosis. The product's IC50 values of 0.1 and 1.2 μM for the inhibition of proteasome and calpain, respectively, highlight its effectiveness. Moreover, MG-132's solubility in DMSO and ethanol ensures compatibility with a wide range of experimental setups. Whether you are studying apoptosis, cell signaling, or protein degradation, MG-132 is an essential addition to your research toolkit.