Viral Puromycin Dihydrochloride, 98%> Collection [eOcZKaBY]

Puromycin Dihydrochloride, 98%

Discover Puromycin Dihydrochloride, a powerful aminonucleoside antibiotic produced by Streptomyces alboniger. This exceptional product is renowned for its potent translational inhibitory effects, making it an invaluable tool in both prokaryotic and eukaryotic cell studies. With a fast mode of action, Puromycin Dihydrochloride causes rapid cell death at low antibiotic concentrations, ensuring efficient and reliable results. Key features include:

• High purity: 98% purity ensures consistent and reliable performance.
• Fast-acting: Rapid cell death at low concentrations for efficient experimentation.
• Selective action: Effective against gram-positive microorganisms and mammalian cells.

Product Properties and Specifications

Puromycin Dihydrochloride boasts a rapid mode of action, causing premature chain termination during translation, effectively disrupting peptide transfer on ribosomes. This antibiotic is highly selective, making it ideal for a variety of research applications. Key specifications include:

• Storage: Store at -20℃ to maintain stability and effectiveness.
• Resistance: Resistance to puromycin is conferred by the puromycin N-acetyl-transferase gene (pac), providing a powerful resistance mechanism.
• Antimicrobial spectrum: Active against gram-positive microorganisms, less active against acid-fast bacilli, and more weakly active against gram-negative microorganisms.

Practical Uses and Benefits

Puromycin Dihydrochloride is a versatile tool for researchers in various fields. Its fast-acting nature and selective action make it ideal for generating puromycin-resistant stable mammalian cell lines in less than one week. This product is particularly beneficial for applications such as bacterial and protozoa growth inhibition, as well as mammalian cell studies. Target audiences include:

• Biologists: For studying protein synthesis and cell biology.
• Pharmacologists: For evaluating the effects of translational inhibitors on cellular processes.
• Microbiologists: For investigating the antimicrobial properties of puromycin.