Must-have H 89, Dihydrochloride Salt, >99% Massive 85% Savings [UJXPR7H3]

H 89, Dihydrochloride Salt, High Purity

Introducing H 89, Dihydrochloride Salt, a premium chemical compound that serves as a potent and selective inhibitor of the three JNK enzymes. This high purity (>99%) product is ideal for research and development in various fields, including pharmaceuticals, cell biology, and biochemistry. With its exceptional effectiveness and specificity, H 89 offers a reliable tool for understanding the complex mechanisms of JNK signaling pathways.

• High purity (>99%) for consistent and reproducible results
• Selective inhibitor of JNK1, JNK2, and JNK3 enzymes
• Competitive inhibitor with respect to ATP, offering a unique mechanism of action

Product Properties and Specifications

H 89, Dihydrochloride Salt, is a versatile research chemical known for its robust inhibitory activity against JNK enzymes. The IC50 values for JNK1, JNK2, and JNK3 are 40nM, 40nM, and 90nM respectively, demonstrating its exceptional selectivity. Its competitive inhibition mechanism ensures that H 89 effectively competes with ATP, making it a powerful tool for studying JNK-dependent signaling pathways. Additionally, this product is stored at -20℃ to maintain its stability and potency.

• IC50 values: JNK1 (40nM), JNK2 (40nM), JNK3 (90nM)
• Competitive inhibitor of JNK enzymes with respect to ATP
• Storage at -20℃ for stability and long-term shelf life

Practical Applications and Benefits

SP600125, also known as H 89, is widely used in scientific research to study the roles of JNK enzymes in various cellular processes. Its ability to inhibit the phosphorylation of c-Jun and subsequent expression of inflammatory genes makes it a valuable tool in understanding inflammation and immune response. Furthermore, H 89's potential to prevent apoptosis and inhibit autophagy in various cell types offers exciting opportunities for exploring new therapeutic approaches in cancer research and other disease models. This product is suitable for researchers, pharmaceutical companies, and academic institutions seeking to delve into the intricate workings of cellular signaling pathways.

• Inhibits the phosphorylation of c-Jun, thereby modulating the expression of inflammatory genes
• Prevents apoptosis and inhibits autophagy in various cell types
• Perfect for research on JNK signaling, inflammation, and apoptosis