Portable Bio, 6-bromoindirubin-3′-oxime Now 90% Cheaper [lW094qeF]

BIO: The Ultimate GSK-3α/β Inhibitor

Introducing 6-Bromoindirubin-3′-Oxime (BIO), a groundbreaking compound that stands out as a potent and reversible GSK-3α/β inhibitor. This innovative molecule is the first pharmacological agent to effectively maintain self-renewal in human and mouse embryonic stem cells, revolutionizing the field of stem cell research. With its ability to keep embryonic stem cells in an undifferentiated state, BIO offers unparalleled potential for scientific advancement and medical breakthroughs.

Key Product Specifications

6-Bromoindirubin-3′-Oxime boasts an impressive IC₅₀ of 5 nM in cell-free assays, demonstrating greater than 16-fold selectivity over CDK5 and other pan-JAK inhibitors. This remarkable specificity makes BIO a highly effective tool for studying the GSK-3α/β signaling pathway. Additionally, BIO targets β-catenin phosphorylation on GSK-3-specific sites, further enhancing its utility in various biological studies. The compound is highly soluble in DMSO, with a concentration of >10 mM, and can be stored at -20℃ for several months without losing its efficacy.

Applications and Benefits

BIO is an indispensable tool for researchers seeking to delve into the complexities of the GSK-3α/β pathway. Its ability to maintain self-renewal in stem cells opens new avenues for studying cellular differentiation and development. Whether you are working on therapeutic interventions, disease modeling, or fundamental biological research, BIO offers numerous benefits. By using BIO, you can achieve the following:

• Enhance stem cell research and differentiation studies
• Gain deeper insights into the GSK-3α/β signaling pathway
• Explore new therapeutic targets for a variety of diseases

With its remarkable properties and versatile applications, BIO is a must-have compound for any laboratory focused on stem cell biology and cellular signaling. Upgrade your research with the power of BIO today.