Top Pick Phorbol 12, 13-dibutyrate, >99% Limited Time 40% Off [M98OaUN4]

High-Quality Phorbol 12, 13-Dibutyrate

Welcome to our premium offering of Phorbol 12, 13-Dibutyrate, a highly pure compound with a purity of >99%. This microbial alkaloid is a powerful tool in the study of cell signaling and is widely recognized for its antifungal activity. Our product stands out due to its exceptional quality and reliability, making it the ideal choice for researchers in various scientific fields.

• High Purity: Our Phorbol 12, 13-Dibutyrate is guaranteed to be >99% pure, ensuring accurate and reproducible results in your experiments.
• Antifungal Properties: This compound exhibits potent antifungal activity, making it a valuable asset in the fight against fungal infections and research on fungal biology.

Pharmacological Profile and Mechanism of Action

Phorbol 12, 13-Dibutyrate interacts with the ATP binding site of various kinases, effectively inhibiting their activity. This interaction is crucial for modulating cellular signaling pathways and is particularly significant in the context of kinase research. Our product has been shown to inhibit a wide range of kinases, including PKA, PKG, MLCK, PKC, CaMK, CAMKII, tyrosine kinases, and phosphorylase kinase, with impressive IC50 values.

• Multiple Kinase Inhibition: Our Phorbol 12, 13-Dibutyrate offers a comprehensive toolkit for studying kinase signaling, with the ability to inhibit various kinases simultaneously.
• Cellular Effects: This compound induces PKC translocation, augments PMA-induced ornithine decarboxylase, and activates a bcl-2-regulated apoptosis pathway, providing a broad spectrum of cellular effects for research applications.

Storage and Handling Instructions

To maintain the integrity and effectiveness of Phorbol 12, 13-Dibutyrate, it is essential to store it properly. Our product should be stored at -20℃ to ensure its stability and longevity. Handling this compound with care is key to achieving reliable and reproducible results in your experiments.

• Optimal Storage Conditions: Store Phorbol 12, 13-Dibutyrate at -20℃ for long-term storage to preserve its purity and efficacy.
• Safe Handling: Handle this compound with caution, as it may be hazardous if not used properly. Always follow appropriate safety protocols and guidelines when working with this product.