All-in-one Kras G12d Protein, Human, Recombinant, Avitag Holiday Edition [9ewYxpIU]

High-Quality KRAS G12D Protein for Oncology Research

The All-in-one Kras G12d Protein, Human, Recombinant, Avitag Holiday Edition [9ewYxpIU]™ is a crucial tool for oncology research, offering a high-quality recombinant protein derived from the human KRAS gene. This protein is a key component of the mitogen-activated protein kinase (MAPK) signaling pathway and is widely recognized for its significance in oncology due to the high occurrence of KRAS mutations in various types of cancers. The protein is produced in E. coli cells and features an N-terminal AviTag™ peptide and His-tag, which allows for site-specific biotinylation using BirA enzyme, enhancing the versatility of your research applications.

• High Purity: The KRAS G12D Protein is purified to >90% purity, ensuring reliable and consistent results.
• Convenient Storage: Store at -70°C to -80°C for long-term stability and minimize freeze/thaw cycles.

Product Features and Specifications

This recombinant KRAS G12D protein offers a range of features that make it an ideal choice for drug development and oncology research. The protein sequence corresponds to amino acids 1 – 185 of the G12D mutant variant of isoform KRAS4B (UNIPROT: P01116-2), providing a reliable and accurate research tool. Additionally, the protein can be loaded with nucleotides or nucleotides' analogs upon request, offering further customization to meet your specific research needs.

• Recombinant Production: Produced in E. coli cells for consistent and reproducible results.
• AviTag™ and His-tag: Allows for site-specific biotinylation and efficient purification.

Applications and Benefits

The KRAS G12D Protein is a valuable resource for researchers studying the MAPK signaling pathway and its role in cancer development. Its high purity, specific tags, and customizable features make it an essential component for various applications, including:

• Drug Development: A crucial target for oncology drug discovery and development.
• Cellular Studies: Facilitates the study of KRAS signaling in cellular models.

Whether you are a researcher in academia or industry, the KRAS G12D Protein is a reliable and versatile tool that will enhance your research efforts. Contact [email protected] for bulk orders or custom packaging to meet your specific requirements.