Today's Deal Cfm-4, Carp-1 Mimetic (tbi1493) For Kids [46wpc7si]

Description

Product Details

Formal Name: 1-[(2-Chlorophenyl)methyl]-5′-phenyl-spiro[3H-indole-3,2′(3’H)-[1,3,4]thiadiazol]-2(1H)-one

Molecular Formula: C₂₂H₁₆ClN₃OS

Formula Weight: 405.90

CAS Number: 331458-02-7

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (greater than 25 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

CARP-1 mimetic

Functions

CARP-1 functional mimetic. Interferes with CARP-1 binding to APC-2 (IC50=10-15 μM). Enhances CARP-1 expression and induces G2/M cell cycle arrest. Induces apoptosis and suppresses growth of medulloblastoma cells and malignant pleural mesothelioma cells.

Application Procedures

First dissolved in DMSO (greater than 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.