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HLA-A3 Monoclonal Antibody (GAP.A3)

The HLA-A3 Monoclonal Antibody (GAP.A3) is a highly specialized tool designed for researchers in the field of immunology and oncology. This antibody, derived from mice, is of the IgG2a kappa isotype and is characterized by its monoclonaclity, ensuring consistent and reliable results across experiments. The GAP.A3 clone specifically targets the human MHC class I molecule HLA-A3, which is a crucial component of the immune system's ability to recognize and respond to antigens.

Product Features and Specifications

This antibody is conjugated with Super Bright™ 436, a fluorescent dye that provides exceptional brightness and long-wavelength emission, making it ideal for flow cytometry analysis. The Super Bright™ 436 dye can be excited with the violet laser line at 405 nm and emits at 436 nm, allowing for high-resolution imaging and data acquisition. The antibody has been pre-diluted and tested for optimal performance in flow cytometric analysis, with a tested dilution of 5 µL (1.0 µg)/test. This convenient format ensures ease of use and consistency in experimental procedures.

Applications and Benefits

The HLA-A3 Monoclonal Antibody (GAP.A3) is particularly valuable for researchers studying the immune response in various contexts, including cancer research. It has been demonstrated to bind the tumor-associated antigen human telomerase reverse transcriptase (hTERT), making it a useful tool for identifying and characterizing cancer cells. The antibody's reactivity with human cells and its application in flow cytometry make it a versatile tool for both basic research and clinical applications. With its high purity achieved through affinity chromatography and its stable formulation in PBS, pH 7.2, containing 0.09% sodium azide, the HLA-A3 Monoclonal Antibody (GAP.A3) is a reliable choice for researchers seeking to advance their understanding of the immune system and its role in disease.

• Applications:
• Flow Cytometry