Most Wishlisted Vsig4 Monoclonal Antibody (jav4), Super Bright™ 600, Ebioscience™ Limited Stock [vdWNqRKU]

Most Wishlisted Vsig4 Monoclonal Antibody (jav4), Super Bright™ 600, Ebioscience™ Limited Stock [vdWNqRKU]

The Most Wishlisted Vsig4 Monoclonal Antibody (jav4), Super Bright™ 600, Ebioscience™ Limited Stock [vdWNqRKU] is a highly specialized reagent designed for in-depth research into the human V-Set and Immunoglobulin domain containing 4 (VSIG4) protein. This antibody, derived from mouse and of the IgG2a, kappa isotype, offers unparalleled specificity and sensitivity in detecting VSIG4, which is also known as Complement Receptor of the Immunoglobulin superfamily (CRIg) or Z39Ig. With its monclonal nature and the JAV4 clone, this antibody is a powerful tool for researchers seeking to understand the complex functions of VSIG4 in the immune system.

Product Features and Specifications

This antibody is formatted with Super Bright™ 600, a fluorescent dye that provides excellent brightness and minimal background noise, making it ideal for flow cytometry applications. The reactivity of this antibody is exclusive to human VSIG4, ensuring that it does not cross-react with mouse or rat VSIG4, thus eliminating potential false positives. The JAV4 antibody recognizes both isoforms of human VSIG4, making it versatile for studying the protein's diverse roles. Key specifications include a tested dilution of 5 µL (0.25 µg)/test and a concentration of 5 µL/Test. The antibody is purified through affinity chromatography, ensuring high purity and consistency.

Applications and Benefits

The Most Wishlisted Vsig4 Monoclonal Antibody (jav4), Super Bright™ 600, Ebioscience™ Limited Stock [vdWNqRKU] is specifically designed for flow cytometric analysis, allowing researchers to visualize and quantify VSIG4 expression in various cell types, including tissue resident and tumor infiltrating macrophages. Its ability to bind complement components C3b and iC3b makes it a valuable tool for studying the alternative complement pathway and phagocytosis. The JAV4 antibody has also been shown to suppress T cell activation, proliferation, and IL-2 production, contributing to the maintenance of peripheral T cell tolerance and the suppression of established inflammation. This versatile antibody is an essential addition to any research lab focused on immunology and inflammation research, offering numerous benefits for both basic and applied research.