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PE/Cyanine7 Anti-Mouse CD154

The PE/Cyanine7 Anti-Mouse CD154 is a highly specialized monoclonal antibody designed for the detection and analysis of CD154, also known as CD40 ligand, on activated CD4⁺ lymphocytes. This antibody is a crucial tool in immunological research, particularly in understanding T-B cell costimulation. The MR1 clone, which this antibody is derived from, has been reported to effectively inhibit the activation of T and B lymphocytes in vitro and antigen-specific lymphocyte responses in vivo. This makes it an invaluable asset for researchers studying immune responses and cellular interactions.

Key Features and Specifications

• Clone: MR1
• Antibody Type: Monoclonal
• Reactivity: Mouse
• Format: PE-Cyanine7
• Host: Armenian Hamster
• Isotype: IgG

The PE-Cyanine7 conjugation allows for excellent fluorescence properties, making this antibody ideal for flow cytometry applications. Its robust binding affinity and specificity ensure reliable results, while its Armenian Hamster origin minimizes the risk of host immunogenicity. This antibody is quality tested for flow cytometry (FC), ensuring its suitability for a wide range of immunological studies.

Applications and Benefits

The PE/Cyanine7 Anti-Mouse CD154 is versatile and suitable for various applications, including flow cytometry. Its ability to inhibit T and B lymphocyte activation makes it particularly useful in exploring the mechanisms of T-B cell costimulation and antigen-specific lymphocyte responses. This product is regulated under RUO (Research Use Only) status, allowing researchers to utilize it in their studies without the need for additional regulatory approval. With detailed technical data sheets available, researchers can confidently incorporate this antibody into their experimental workflows, streamlining their research processes and enhancing their ability to uncover the complexities of the immune system.