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PE/Cyanine7 Anti-Human CD86 Antibody

Our PE/Cyanine7 Anti-Human CD86 Antibody is a powerful tool for researchers studying immune responses and T cell activation. This monoclonal antibody, clone IT2.2, is designed to detect and analyze CD86, a crucial molecule in the immune system. Known as B7-2, B70, and Ly-58, CD86 is expressed on various immune cells, including activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. This antibody offers a high level of specificity and sensitivity, making it ideal for flow cytometry and other cellular analysis techniques.

Product Specifications

The PE/Cyanine7 Anti-Human CD86 Antibody is a mouse monoclonal antibody with an IgG2b, κ isotype. It is conjugated to PE-Cyanine7, a vibrant fluorescent dye that provides excellent signal strength and minimal bleed-through. This antibody is reactive with human, cynomolgus, and rhesus samples, making it versatile for a wide range of applications. The antibody has been quality tested for flow cytometry (FC), ensuring reliable results in your experiments. Additionally, it is supplied in a sterile format, eliminating the risk of contamination.

Applications and Benefits

The PE/Cyanine7 Anti-Human CD86 Antibody is an essential reagent for researchers investigating immune regulation and T cell function. Its ability to bind to CD86 on various immune cells allows for the analysis of T cell activation, proliferation, and cytokine production. This antibody is particularly useful in studying the early stages of the immune response, as CD86 is expressed earlier than its ligand, CD80. Moreover, its ability to bind to CD152 (CTLA-4) provides a means to deliver inhibitory signals to T cells, which is crucial for understanding immune tolerance and suppression. Whether you are exploring the intricacies of the immune system or developing new therapies, this antibody is a valuable addition to your laboratory toolkit.