Crowd Pleaser Percp/cyanine5.5 Anti-human Cd223 (lag-3) For Kids [8cQkTsul]

Highly Sensitive CD223 Antibody for Advanced Research

The Crowd Pleaser Percp/cyanine5.5 Anti-human Cd223 (lag-3) For Kids [8cQkTsul] antibody is a powerful tool for researchers investigating T-cell signaling and immune regulation. This monoclonal antibody, clone 11C3C65, offers exceptional specificity and sensitivity for detecting and analyzing CD223, also known as LAG-3, a crucial glycoprotein in the immune response.

• High Affinity: Similar to CD4, CD223 binds MHC class II with a higher affinity, making this antibody ideal for identifying and studying this protein.
• Multiple Applications: The antibody is well-suited for flow cytometry, enabling detailed analysis of T-cells, natural killer cells, and regulatory T-cells.

Key Features and Specifications

This product is manufactured by BioLegend, Inc., a trusted name in the field of immunology research. The antibody is formatted in PerCP-Cyanine5.5, a bright and photostable dye, ensuring optimal signal generation and reduced background.

• Host Species: Mouse IgG1, κ
• Reactivity: Human
• Applications: Flow Cytometry (FC)

The regulatory status of this product is RUO (Research Use Only), making it suitable for a wide range of research applications without the need for clinical validation.

Applications and Benefits

The Crowd Pleaser Percp/cyanine5.5 Anti-human Cd223 (lag-3) For Kids [8cQkTsul] antibody is invaluable for studying the role of CD223 in T-cell activation and regulation, particularly in the context of cancer and viral infections.

• Enhanced T-cell Activation: CD223 negatively regulates T-cell activation, making it a key factor in maintaining immune homeostasis.
• Therapeutic Potential: CD223 deficiency has been associated with reduced tumor growth, suggesting potential therapeutic applications.

This antibody is also suitable for exploring the synergy between CD223 and PD-1, which can reverse exhausted phenotypes and improve tumor rejection.