Premium Quality Brilliant Violet 421™ Anti-mouse Il-33rα (il1rl1, St2) Bundle [QOqkVgL1]

Brilliant Violet 421™ Anti-Mouse IL-33Rα (IL1RL1, ST2)

The Premium Quality Brilliant Violet 421™ Anti-mouse Il-33rα (il1rl1, St2) Bundle [QOqkVgL1] antibody is a powerful tool for researchers studying the IL-33Rα pathway. This monoclonal antibody, clone DIH9, offers a highly specific and reliable way to detect and analyze IL-33Rα, a key player in the Toll/IL-1 receptor family. The antibody is formatted in BV421, a vibrant and highly photostable dye, making it ideal for flow cytometry applications.

Product Features and Specifications

This antibody is produced by BioLegend, Inc., a trusted provider of high-quality research reagents. It is a monoclonal antibody of the IgG2a isotype and is reactive against mouse IL-33Rα. The antibody is conjugated to BV421, a fluorescent dye that emits light at 421 nm when excited by a laser. This conjugation allows for clear and distinct staining in flow cytometry experiments. The product is also available in a convenient format for easy handling and storage.

Practical Applications

The IL-33Rα-ST2 axis is a critical target in various diseases, including asthma, allergies, and cardiac disease. By blocking IL-33Rα with anti-ST2 antibodies, researchers have shown promising results in alleviating experimental arthritis and airway inflammation. This antibody can be used to study the role of IL-33Rα in these diseases and to develop potential therapeutic strategies. The following are some key benefits of using this antibody:

High specificity: The DIH9 clone offers a high level of specificity for IL-33Rα, reducing the risk of cross-reactivity.

Multi-color compatibility: The BV421 conjugation allows for easy integration into multi-color flow cytometry panels.

Quality tested: This antibody has been quality tested for flow cytometry applications, ensuring reliable results.