Ultimate Brilliant Violet 510™ Anti-human Cd195 (ccr5) Device [9yEzikf1]

Brilliant Violet 510™ Anti-Human CD195 (CCR5)

The Ultimate Brilliant Violet 510™ Anti-human Cd195 (ccr5) Device [9yEzikf1] antibody is a powerful tool for researchers studying the crucial role of CCR5 in various human diseases. This monoclonal antibody offers exceptional specificity and sensitivity, making it ideal for flow cytometry applications.

Product Details

This antibody, clone J418F1, is a monoclonal antibody of the IgG2b isotype and κ chain. It is designed to bind specifically to human CD195, also known as CCR5, a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. The antibody recognizes human cells and is formatted in BV510, a highly sensitive fluorescent dye. Key features include:

Reactivity: Human

Format: BV510

Host: Rat

Applications: Flow Cytometry (FC)

Applications and Benefits

The Ultimate Brilliant Violet 510™ Anti-human Cd195 (ccr5) Device [9yEzikf1] antibody is a versatile reagent for investigating CCR5's role in a wide range of diseases, including infectious, inflammatory, and even cancerous conditions. Its high affinity and specificity make it an excellent choice for researchers seeking to understand the complex interactions between CCR5 and its ligands, such as MIP-1α, MIP-1β, and RANTES. This antibody is particularly valuable for studies on HIV-1 entry, as CCR5 acts as a co-receptor for R5 HIV-1 cell entry. By using this antibody, researchers can:

Identify and characterize CCR5-expressing cells

Assess the role of CCR5 in disease progression

Develop novel therapeutic strategies targeting CCR5

With its robust performance and broad applicability, this antibody is a must-have for any laboratory focused on immunology and infectious diseases research.