Multi-purpose Brilliant Violet 421™ Anti-human Ikaros Upgraded Model [O2JNWS0r]

Brilliant Violet 421™ Anti-Human Ikaros

The Multi-purpose Brilliant Violet 421™ Anti-human Ikaros Upgraded Model [O2JNWS0r] is a highly specialized monoclonal antibody designed to detect and analyze the expression of the Ikaros protein in human cells. Ikaros, also known as IKZF1, is a crucial zinc-finger DNA-binding protein that plays a pivotal role in lymphocyte differentiation. This antibody is an invaluable tool for researchers studying hematopoietic cell types, including T- and B-cells, natural killer cells (NKs), monocytes/macrophages, and dendritic cells. The Ikaros protein is a tumor suppressor, and its absence or reduced expression has been linked to several leukemias, making this antibody essential for investigating the molecular mechanisms underlying these diseases.

• Monoclonal Antibody: The 16B5C71 clone ensures specificity and reproducibility in your experiments.
• Human Reactivity: This antibody is tailored for human applications, providing reliable results in human cell research.

Product Properties and Specifications

The Multi-purpose Brilliant Violet 421™ Anti-human Ikaros Upgraded Model [O2JNWS0r] offers several key properties and specifications that make it a preferred choice in research laboratories. This monoclonal antibody is conjugated to the vibrant Brilliant Violet 421™ dye, which emits a strong and bright fluorescence under excitation at 405 nm. This allows for clear visualization and analysis in flow cytometry and fluorescence microscopy. The antibody is derived from mouse and is of the IgG2a isotype, with a κ light chain. The format is ready-to-use, eliminating the need for conjugation and simplifying experimental procedures.

• Host and Isotype: Mouse IgG2a, κ
• Format: BV421-conjugated, ready-to-use

The product has been quality tested for intracellular cytokine staining (ICFC), ensuring its performance in various cellular applications.

Practical Uses and Target Audience

The Multi-purpose Brilliant Violet 421™ Anti-human Ikaros Upgraded Model [O2JNWS0r] is an indispensable tool for researchers in the fields of hematology, immunology, and oncology. Its ability to detect Ikaros protein expression in a variety of hematopoietic cell types makes it particularly valuable for studies on lymphoid differentiation and leukemogenesis. This antibody is also suitable for assessing the efficacy of targeted therapies and for understanding the role of Ikaros in immune responses. Ideal users of this product include scientists working in academic research institutions, biotech companies, and pharmaceutical organizations.

• Target Audience: Hematologists, immunologists, oncologists, and researchers in related fields
• Applications: Flow cytometry, fluorescence microscopy, and other cellular analysis techniques

With its comprehensive product information, including Technical Data Sheets (TDS) and Safety Data Sheets (SDS), the Multi-purpose Brilliant Violet 421™ Anti-human Ikaros Upgraded Model [O2JNWS0r] provides researchers with all the necessary resources for successful experiments.