Believe It Brilliant Violet 750™ Anti-human Cd223 (lag-3) Holiday Edition [5GlKqgTv]

Brilliant Violet 750™ Anti-Human CD223 (LAG-3)

The Believe It Brilliant Violet 750™ Anti-human Cd223 (lag-3) Holiday Edition [5GlKqgTv] antibody is a powerful tool for researchers studying T-cell signaling and its role in immune responses. This monoclonal antibody, clone 11C3C65, is specifically designed for the detection of CD223, also known as LAG-3, on the surface of human cells. CD223 is a type I transmembrane glycoprotein that plays a crucial role in T-cell activation and regulation. It binds to MHC class II molecules with higher affinity than CD4, thereby negatively regulating T-cell activation. This antibody is a valuable resource for investigating the complex interplay between T-cells and the immune system.

Product Features and Specifications

The Believe It Brilliant Violet 750™ Anti-human Cd223 (lag-3) Holiday Edition [5GlKqgTv] antibody is produced using a mouse IgG1, κ isotype. It is formatted in BV750 conjugation, offering exceptional brightness and long-wavelength emission for optimal visualization in flow cytometry. This antibody has been quality tested for flow cytometry (FC) applications, ensuring reliable and consistent results. Its reactivity is exclusive to human cells, making it ideal for use in human research. The regulatory status of this product is RUO (Research Use Only), making it suitable for a wide range of experimental settings.

Practical Applications and Benefits

The Believe It Brilliant Violet 750™ Anti-human Cd223 (lag-3) Holiday Edition [5GlKqgTv] antibody is highly versatile and can be used to study various aspects of T-cell biology. Its ability to detect CD223 expression on activated T-cells, natural killer cells, and regulatory T-cells makes it an invaluable tool for understanding immune responses and the mechanisms behind them. CD223 deficiency has been associated with reduced tumor growth, highlighting the potential therapeutic implications of this research. Additionally, the synergistic interaction between CD223 and PD-1 can reverse exhausted phenotypes, improve tumor rejection, and control viral load, offering new avenues for cancer immunotherapy and antiviral research. With its robust performance and wide range of applications, this antibody is a must-have for any researcher involved in T-cell biology and immunology.