Ultimate Brilliant Violet 750™ Anti-human Cd127 (il-7rα) Accessory [2GUYhisN]

Brilliant Violet 750™ Anti-Human CD127 (IL-7Rα)

The Ultimate Brilliant Violet 750™ Anti-human Cd127 (il-7rα) Accessory [2GUYhisN] is a high-performance monoclonal antibody designed for immunofluorescence (IF) and flow cytometry applications. This antibody targets the CD127 glycoprotein, a crucial marker for identifying and distinguishing various cell types within the immune system. With its unique fluorescent properties, the Brilliant Violet 750™ conjugate offers enhanced detection and visualization, making it an ideal tool for in-depth immunophenotyping studies.

Product Details

This monoclonal antibody, clone A019D5, is derived from a mouse host and has an IgG1, κ isotype. It is specifically reactive to human CD127, a type I transmembrane glycoprotein that forms a heterodimer with the common γ chain. CD127 is expressed on a variety of cell types, including immature B cells, thymocytes, peripheral T cells, and bone marrow stromal cells. The product is available in a BV750 format, offering excellent brightness and long-wavelength emission for fluorescence microscopy. Here are some key features and specifications:

• Host: Mouse
• Reactivity: Human
• Applications: Flow Cytometry, Immunofluorescence

Applications and Benefits

The Ultimate Brilliant Violet 750™ Anti-human Cd127 (il-7rα) Accessory [2GUYhisN] is an invaluable tool for researchers studying immune cell development and function. It can be used to differentiate between various cell subsets, such as memory and effector T cells, as well as regulatory T cells (Tregs). The down-modulation of CD127 expression on Tregs makes it a valuable marker for distinguishing these cells from conventional T cells. This product is particularly useful in the following scenarios:

• Immune Cell Profiling: Characterize and enumerate different immune cell populations in complex samples.
• Immunophenotyping: Identify and analyze T cells, B cells, and other lymphoid cell subsets.

Its versatile application in immunology research and its ability to provide detailed insights into immune cell populations make it a must-have tool for any laboratory focused on understanding the complexities of the immune system.