Value Buy Brilliant Violet 510™ Anti-mouse/human Cd45r/b220 Accessory [ORpwEDW6]

Brilliant Violet 510™ CD45R/B220 Antibody

Discover the ultimate tool for immune cell analysis with the Value Buy Brilliant Violet 510™ Anti-mouse/human Cd45r/b220 Accessory [ORpwEDW6] antibody. This monoclonal antibody, clone RA3-6B2, is a powerful reagent for identifying and studying B cells, activated B cells, and subsets of T and NK cells. With its broad reactivity to both mouse and human samples, it is an essential component for research involving immune system functions and diseases.

Product Properties and Specifications

The CD45R/B220 antibody is a highly specific marker for B cells, offering unparalleled accuracy in cell sorting and flow cytometry applications. Its molecular weight of approximately 180-240 kD and BV510 conjugation make it ideal for detection using a range of fluorescence-activated cell sorters. The antibody is derived from a rat host and is of the IgG2a, κ isotype, ensuring compatibility with various immunological assays. Key features include:

Monoclonal antibody clone RA3-6B2

Reactivity to mouse and human samples

BV510 conjugation for enhanced fluorescence

Applications: Flow Cytometry, Immunohistochemistry (IHC-F)

Practical Applications and Benefits

The Value Buy Brilliant Violet 510™ Anti-mouse/human Cd45r/b220 Accessory [ORpwEDW6] antibody is an invaluable resource for researchers studying B cell development, activation, and function. It is particularly useful in identifying subsets of T and NK cells and in the analysis of abnormal T cells associated with systemic autoimmunity in certain mouse models. The antibody's reported applications include:

Flow Cytometry: Accurate cell sorting and characterization of B cells

Immunohistochemistry: Visualization of B cell markers in tissue sections

Research in autoimmunity and immune system disorders

Development of diagnostic and therapeutic strategies