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PE Anti-GATA3: A Potent Tool for Immune Cell Research

The PE Anti-GATA3 is a highly specialized monoclonal antibody designed for researchers studying the crucial role of GATA3 in immune cell differentiation. This antibody targets the human and mouse GATA3 proteins, making it a versatile tool for various experimental settings. Its PE conjugation provides exceptional brightness and multiplexing capabilities, allowing for detailed analysis of GATA3 expression in complex samples.

Product Details and Specifications

The PE Anti-GATA3, clone 16E10A23, is a mouse monoclonal antibody with a PE (phycoerythrin) conjugation. It is designed to bind specifically to GATA3, a key regulator of T helper 2 (Th2) cell differentiation. The antibody has been validated for use in flow cytometry (ICFC), offering high sensitivity and specificity. Its host is a mouse, and the isotype is IgG2b, κ. This product is supplied by BioLegend, Inc., and comes with detailed data sheets for technical specifications and safety data.

Applications and Benefits

The PE Anti-GATA3 is an essential tool for researchers investigating the function of GATA3 in immune cell development and malignancy. Its applications include the analysis of Th2 cell differentiation, T cell commitment, and the role of GATA3 in breast cancer development. With its high reactivity to human and mouse samples, this antibody is suitable for both basic research and translational studies. Key benefits include its PE conjugation for multiplexing, validated ICFC application, and the ability to explore the role of GATA3 in various immune-related diseases and conditions.