Warehouse Clearance Alexa Fluor® 647 Anti-human Cd337 (nkp30) Device [pM4XK2kZ]

Introducing Alexa Fluor® 647 Anti-Human CD337 (NKp30)

The Alexa Fluor® 647 Anti-Human CD337 (NKp30) monoclonal antibody, clone P30-15, is a powerful tool for researchers studying the NKp30 receptor and its role in immune responses. This antibody specifically recognizes CD337, also known as activating NK receptor NKp30 or natural cytotoxicity triggering receptor 3, making it ideal for a wide range of applications. With its high specificity and affinity, this antibody is a valuable asset in flow cytometry, cell stimulation, and function blocking assays.

Product Specifications and Features

The P30-15 monoclonal antibody is produced in mice and conjugated to Alexa Fluor® 647, a highly sensitive fluorescent dye that emits bright, near-infrared fluorescence. This format ensures excellent signal-to-noise ratios and allows for multiplexing with other fluorophores. The antibody recognizes NKp30, a type I transmembrane protein expressed on resting and activated NK cells, and is known to enhance NK cell cytolysis of tumor cells lacking MHC class I molecules. Key features include:

• Monoclonal Antibody Type: IgG1, κ
• Reactivity: Human
• Format: Alexa Fluor® 647 Conjugated
• Applications: Flow Cytometry, NK Cell Stimulation, Function Blocking

Practical Applications and Benefits

The Alexa Fluor® 647 Anti-Human CD337 (NKp30) antibody is a versatile tool for researchers in the fields of immunology, oncology, and cellular biology. Its ability to enhance NK cell cytolysis and block NKp30 function makes it particularly valuable for studies involving NK cell function and tumor immunity. This antibody is suitable for use in flow cytometry, where it can be used to detect and analyze NKp30 expression on NK cells. Additionally, it can be employed in redirected lysis assays to stimulate NK cells via NKp30, providing a valuable tool for understanding NK cell responses. Whether you are studying NK cell biology, tumor immunity, or the role of NKp30 in immune regulation, this antibody is an essential resource.