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APC Anti-Human CD42b Antibody

The APC Anti-Human CD42b Antibody is a highly specialized monoclonal antibody designed for research applications in immunology and hematology. This antibody targets the CD42b glycoprotein, also known as gpIbα, which is a crucial component of the GPIb complex. The CD42b/c heterodimer, when combined with CD42a and d, forms a complex that acts as a receptor for von Willebrand factor and thrombin, playing a pivotal role in platelet adhesion and clot formation. This antibody is a valuable tool for researchers studying platelet and megakaryocyte biology, as well as the pathophysiology of thrombotic disorders.

Product Specifications and Features

The APC Anti-Human CD42b Antibody is produced using a mouse monoclonal IgG1 κ isotype. It is conjugated to the APC fluorochrome, providing a vibrant and highly visible signal for flow cytometry analysis. The antibody has been tested and validated for its functionality in fluorescence-activated cell sorting (FACS) applications, ensuring reliable and consistent results. Key features of this product include:

Monoclonal antibody targeting CD42b/gpIbα

APC conjugation for vibrant fluorescence

Mouse IgG1 κ isotype

Quality tested for FACS applications

Applications and Benefits

The APC Anti-Human CD42b Antibody is an essential reagent for researchers investigating platelet function, thrombosis, and related diseases. Its ability to specifically bind to CD42b on platelets and megakaryocytes makes it ideal for a variety of applications, including:

Characterization of platelet surface markers

Assessment of platelet activation and aggregation

Study of thrombotic disorders and bleeding syndromes

By using this antibody, researchers can gain valuable insights into the complex processes involved in hemostasis and thrombosis, leading to a better understanding of these conditions and potential therapeutic strategies.