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APC/Cyanine7 Anti-Mouse/Rat XCR1 Antibody

The APC/Cyanine7 Anti-Mouse/Rat XCR1 Antibody is a highly specialized tool designed for researchers studying the crucial role of XCR1 in immune responses. This monoclonal antibody, clone ZET, offers exceptional specificity and sensitivity, making it an ideal choice for applications such as flow cytometry. Its reactivity with both mouse and rat samples ensures versatility in research settings.

Product Specifications and Features

This antibody is a monoclonal of the IgG2b isotype and is conjugated with APC-Cyanine7, a vibrant fluorescent dye known for its high sensitivity and excellent compatibility with flow cytometry. The host species is mouse, and it has been quality tested for functional applications. The antibody recognizes the XCR1 receptor, also known as GPR5 or CCXCR1, which is a G-protein coupled receptor with seven transmembrane domains. Key features include:

• Reactivity: Mouse, Rat
• Format: APC-Cyanine7 conjugated
• Host: Mouse
• Isotype: IgG2b, κ
• Applications: Flow Cytometry (FC)

Applications and Benefits

The APC/Cyanine7 Anti-Mouse/Rat XCR1 Antibody is a powerful tool for investigating the function of XCR1 in various biological processes, particularly in the context of CD8α⁺ conventional dendritic cells. Its ability to mediate chemotaxis of XCL1 and XCL2, and define antigen-presenting cells, makes it invaluable for researchers studying immune responses. This antibody is suitable for use in flow cytometry, allowing for detailed analysis of cell surface markers. By utilizing this product, researchers can:

• Enhance: Immune response studies with high specificity and sensitivity
• Improve: Understanding of antigen cross-presentation in dendritic cells
• Enable: Detailed analysis of XCR1-expressing cells