Time Saver Human Il-4 Recombinant Protein His Tag Lyophilized - Us Warehouse [cCgLvM05]

Time Saver Human Il-4 Recombinant Protein His Tag Lyophilized - Us Warehouse [cCgLvM05] from Innovative Research has been recombinantly produced in E. coli. This is a Lyophilized protein buffered in Lyophilized from 0.2um-filtered solution in PBS (pH 7.4). Reconstituted in sterile H2O not less than 100 and#956;g/ml, which can then be further diluted in other aqueous solutions. with a purity of >98% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ and#956;g protein (LAL test; Lonza)..

More Details:

• Species: Human
• Target: IL4
• Purity: >98% (SDS-PAGE).
  
  Endotoxin level is less than 0.1EU/ and#956;g protein (LAL test; Lonza).
• Source: E. coli
• Storage Conditions: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Additional Information:

Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.

This recombinant proteins is for research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.