Must-see Human April Recombinant Protein Lyophilized - Ships Same Day [woAVSaHE]

Must-see Human April Recombinant Protein Lyophilized - Ships Same Day [woAVSaHE] from Innovative Research has been recombinantly produced in High-5 Insect cells. This is a Lyophilized protein buffered in with a purity of Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per and#956;g (1EU/and#956;g)..

More Details:

• Species: Human
• Target: TNFSF13
• Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses.
  
  Endotoxin level is less than 0.1 ng per and#956;g (1EU/and#956;g).
• Source: High-5 Insect cells
• Storage Conditions: The lyophilized APRIL recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted APRIL is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing APRIL recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Additional Information:

APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. APRIL, along with another TNF family member, BAFF, compete for two receptors, TACI and BCMA. ARPIL has the ability to stimulate proliferation of various tumor cell lines including Jurkat T cells and MCF-7 carcinoma cells. Like BAFF, APRIL also stimulates the proliferation of B and T cells. The human APRIL gene codes for at least four alternatively spliced transcriptional variants, which give rise to different isoforms of the APRIL precursor protein. All isoforms can be cleaved by the protease, furin, to release a soluble C-terminal fragment, which comprises the TNF like receptor binding of the APRIL precursor. Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues.

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