Bacteria-Derived Alpha-Synuclein Recombinant Protein Lyophilized from Innovative Research has been recombinantly produced in E.coli. The protein formulation is lyophilized from a 0.2 ?m filtered solution of PBS;PH7.4. with a purity of > 95% as determined by reducing SDS-PAGE..More Details: Species: Human Target: Alpha-Synuclein Purity: > 95% as determined by reducing SDS-PAGE..< 1.0 EU per ?g as determined by the LAL method. Source: E.coli Storage Conditions: Lyophilized proteins are stable for up to 12 months when stored at -20 to -80░C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20? for 3 months. Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1; Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition; SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.For research use only.
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