Last Chance Rabbit Anti Human Bcl10 Polyclonal Affinity Purified (pbs With 0.02% Sodium Azide, 50% Glycerol, Ph7.3) (western Blot) Get 70% Off Today [yEbuAj6B]

Last Chance Rabbit Anti Human Bcl10 Polyclonal Affinity Purified (pbs With 0.02% Sodium Azide, 50% Glycerol, Ph7.3) (western Blot) Get 70% Off Today [yEbuAj6B] from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 50% glycerol, pH7.3 This antibody has been affinity purified.

More Details:

• Host: Rabbit
• Species: Human
• Target: BCL10
• Clonality: Polyclonal
• Purity: Affinity Purified
• Immunogen: Recombinant fusion protein of human BCL10 (NP_003912.1).
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.

This product can be used in analytical tools such as Western Blot.

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For research use only.