New Arrival Rabbit Anti Human Mc1r Polyclonal Affinity Purified (pbs With 0.05% Sodium Azide And 50% Glycerol, Ph7.4) (western Blot,elisa) Massive 70% Savings [7opRkGSh]

New Arrival Rabbit Anti Human Mc1r Polyclonal Affinity Purified (pbs With 0.05% Sodium Azide And 50% Glycerol, Ph7.4) (western Blot,elisa) Massive 70% Savings [7opRkGSh] from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.05% sodium azide and 50% glycerol, pH7.4 This antibody has been purified using Affinity Purified.

More Details:

• Host: Rabbit
• Species: Human,Mouse
• Target: MC1R
• Clonality: Polyclonal
• Purity: Affinity Purified
• Immunogen: Synthetic peptide of human MC1R
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation.

This product can be used in analytical tools such as Western Blot,ELISA.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.