Hot Item Rabbit Anti Human Kcnip3 Polyclonal Antigen Affinity Purified (pbs With 0.05% Sodium Azide And 40% Glycerol, Ph7.4) (ihc,elisa) Holiday Cheer Edition [kz0bCU43]

Hot Item Rabbit Anti Human Kcnip3 Polyclonal Antigen Affinity Purified (pbs With 0.05% Sodium Azide And 40% Glycerol, Ph7.4) (ihc,elisa) Holiday Cheer Edition [kz0bCU43] from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.05% sodium azide and 40% Glycerol, pH7.4 This antibody has been purified using Antigen Affinity Purified.

More Details:

• Host: Rabbit
• Species: Human, Mouse, Rat
• Target: KCNIP3
• Clonality: Polyclonal
• Purity: Antigen Affinity Purified
• Immunogen: Fusion protein of human KCNIP3
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3) is a Protein Coding gene. Diseases associated with KCNIP3 include Alzheimer Disease. Among its related pathways are Cardiac conduction and Development Ligand-independent activation of ESR1 and ESR2. GO annotations related to this gene include calcium ion binding and transcription corepressor activity. An important paralog of this gene is KCNIP4.

This product can be used in analytical tools such as IHC,ELISA.

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For research use only.