Fan Favorite Rabbit Anti Hla-dqa1 Polyclonal Affinity Purified (pbs With 0.02% Sodium Azide, 50% Glycerol, Ph7.3) (western Blot,ihc) See Details [YbPqdDaw]

Fan Favorite Rabbit Anti Hla-dqa1 Polyclonal Affinity Purified (pbs With 0.02% Sodium Azide, 50% Glycerol, Ph7.3) (western Blot,ihc) See Details [YbPqdDaw] from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 50% glycerol, pH7.3 This antibody has been affinity purified.

More Details:

• Host: Rabbit
• Species: Human,Mouse
• Target: HLA-DQA1
• Clonality: Polyclonal
• Purity: Affinity Purified
• Immunogen: Recombinant fusion protein of human HLA-DQA1 (NP_002113.2).
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.

This product can be used in analytical tools such as Western Blot,IHC.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.