Clinically Tested Rabbit Anti Dusp4 Polyclonal Affinity Purified (pbs With 0.05% Sodium Azide And 50% Glycerol, Ph7.4) (western Blot,ihc,elisa) Trusted Seller [PkWGK5yx]

Clinically Tested Rabbit Anti Dusp4 Polyclonal Affinity Purified (pbs With 0.05% Sodium Azide And 50% Glycerol, Ph7.4) (western Blot,ihc,elisa) Trusted Seller [PkWGK5yx] from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.05% sodium azide and 50% glycerol, pH7.4 This antibody has been affinity purified.

More Details:

• Host: Rabbit
• Species: Human,Mouse,Rat
• Target: DUSP4
• Clonality: Polyclonal
• Purity: Affinity Purified
• Immunogen: Recombinant protein of human DUSP4
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.

This product can be used in analytical tools such as Western Blot,IHC,ELISA.

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For research use only.