Member Exclusive Rabbit Anti Raf1 Polyclonal Affinity Purified (pbs With 0.02% Sodium Azide, 50% Glycerol, Ph7.3) (western Blot,ihc,immunofluorescence) Certified [xj3DQyrU]

Member Exclusive Rabbit Anti Raf1 Polyclonal Affinity Purified (pbs With 0.02% Sodium Azide, 50% Glycerol, Ph7.3) (western Blot,ihc,immunofluorescence) Certified [xj3DQyrU] from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 50% glycerol, pH7.3 This antibody has been affinity purified.

More Details:

• Host: Rabbit
• Species: Human,Mouse,Rat
• Target: RAF1
• Clonality: Polyclonal
• Purity: Affinity Purified
• Immunogen: Recombinant fusion protein of human RAF1 (NP_002871.1).
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.

This product can be used in analytical tools such as Western Blot,IHC,Immunofluorescence.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.