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Thalidomide-Propargyl-O-PEG2-OH: A Cutting-Edge Degrader Building Block

Thalidomide-Propargyl-O-PEG2-OH is a highly sophisticated degrader building block designed for targeted protein degradation. This innovative compound combines the power of an E3 ligase ligand with a versatile linker and a reactive function group, enabling straightforward conjugation to target protein ligands. Its unique structure and functional properties make it an essential tool for researchers in the field of targeted protein degradation.

• Highly Effective: Thalidomide-Propargyl-O-PEG2-OH demonstrates exceptional efficiency in degrading specific proteins, providing a robust tool for in vitro and in vivo research.
• Easy to Use: The straightforward conjugation process allows for quick and efficient synthesis of targeted protein degradation constructs.

Technical Specifications and Properties

This product boasts a molecular formula of C20H20N2O7 and a molecular weight of 400.387 g/mol. With a high purity of >= 95% as determined by HPLC, Thalidomide-Propargyl-O-PEG2-OH ensures reliable and consistent performance. The compound is stable under room temperature conditions and should be stored refrigerated to maintain its integrity.

• CAS Number: Not available.
• Shipping Conditions: Room temperature.
• Storage Conditions: Refrigerated.

Applications and Benefits

Thalidomide-Propargyl-O-PEG2-OH finds extensive applications in various research fields, including drug discovery, proteomics, and personalized medicine. By enabling targeted protein degradation, this building block offers numerous benefits, such as:

• Enhanced Drug Efficacy: Facilitates the development of novel therapeutic agents that can specifically degrade disease-causing proteins.
• Improved Understanding of Protein Functions: Enables researchers to study the role of specific proteins in cellular processes and disease progression.

Targeted researchers in academia and pharmaceutical industries will find Thalidomide-Propargyl-O-PEG2-OH an invaluable asset for advancing their studies in targeted protein degradation.