Portable Urokinase Human Purified Protein Best Choice [Wu9tki06]

Description

Portable Urokinase Human Purified Protein Best Choice [Wu9tki06] is a two-chain glycoprotein containing 411 amino acids with 12 disulfide bonds. It has a molecular weight of 54,000 Dalton. 

Urokinase, also known as urokinase-type plasminogen activator, is a serine protease that specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. It is involved in numerous biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing.

Synonyms

EC:3.4.21.73, urokinase-type plasminogen activator, UK, U-plasminogen activator, uPA.

Source

The enzyme is purified from human urine.

Formulation

Reconstitution

It is recommended to reconstitute the lyophilized urokinase in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

Purity

Greater than 85.0%.

Specific Activity

187,973 IU/mg (may vary slightly with each lot, please refer to the enclosed Certificate of Analysis with your product).

Contaminants

Free of: Hepatitis B surface antigen, Hepatitis C antibody, HIV I and HIV II.

Shipping & Storage

Ships at ambient temperature. Upon receipt, store the product at the temperature recommended below:

Lyophilized urokinase, although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution, urokinase should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.

Documents

• Product Datasheet (PDS)