Festive Deal Recombinant Mouse Il-17a Protein (his Tag)(active) - Don't Overpay [PhjbHO8l]

Recombinant Mouse IL-17A Protein: A Potent Tool for Research

The Festive Deal Recombinant Mouse Il-17a Protein (his Tag)(active) - Don't Overpay [PhjbHO8l] is a powerful research tool designed for use in various cellular assays and applications. This active protein, expressed in HEK293 cells, is an essential component for studying interleukin-17A, a crucial pro-inflammatory cytokine. With its high purity (>95%) and low endotoxin content (<0.01 EU per μg), this protein ensures reliable and reproducible results in your experiments. Its bio-activity is measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells, with an ED50 of 0.25-1.25 ng/ml.

Key Features and Specifications

This recombinant protein is characterized by its sequence Thr22-Ala158 and has a calculated molecular weight of 16.2 kDa, observed as 17-26 kDa. It is tagged with a C-His tag for easy detection and purification. The protein is produced in a mammalian expression system, ensuring high biological activity and functionality. Its purity is guaranteed to be greater than 95% as determined by reducing SDS-PAGE, and it meets stringent endotoxin standards. The protein is lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, and is typically formulated with 5%-8% trehalose, mannitol, and 0.01% Tween 80 as protectants.

Applications and Benefits

The Recombinant Mouse IL-17A Protein is a valuable resource for researchers investigating inflammatory diseases, particularly those involving joint inflammation and bone and cartilage destruction. It is ideal for use in cellular assays, immunoprecipitation, and other in vitro applications. This protein can help researchers better understand the role of interleukin-17A in various pathological conditions, such as rheumatoid arthritis. By providing a reliable source of this critical cytokine, this product empowers scientists to advance their research and develop new treatments for inflammatory diseases.