Ultimate Recombinant Mouse Igg2a-fc Protein (aa 99-330) - Today Only [RoUk6G54]

Ultimate Recombinant Mouse Igg2a-fc Protein (aa 99-330) - Today Only [RoUk6G54]

Our Ultimate Recombinant Mouse Igg2a-fc Protein (aa 99-330) - Today Only [RoUk6G54] is a high-quality recombinant protein derived from HEK293 cells. This protein is a crucial component of the IgG2a isotype, which plays a significant role in the secondary antibody response and is the only isotype capable of passing through the human placenta. This makes it an invaluable tool for research and development in the fields of immunology and biotechnology.

Product Specifications and Properties

The Ultimate Recombinant Mouse Igg2a-fc Protein (aa 99-330) - Today Only [RoUk6G54] is expressed in HEK293 cells, ensuring high purity and consistent quality. This protein has a calculated molecular weight of 26.7 kDa and an observed molecular weight of 31-37 kDa. It is >95% pure, as determined by reducing SDS-PAGE, and contains < 1.0 EU per μg of protein as determined by the LAL method. The protein is lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, with added protectants such as trehalose, mannitol, and Tween 80 for stability. This product is suitable for various applications, including research and development in immunology, biotechnology, and drug discovery.

Applications and Benefits

The Ultimate Recombinant Mouse Igg2a-fc Protein (aa 99-330) - Today Only [RoUk6G54] is a versatile tool for researchers studying the immune response and antibody-mediated functions. Its high purity and specific sequence make it ideal for use in affinity purification, immunoprecipitation, and as a control in various assays. This protein can also be used to study the Fc region of IgGs, which is involved in mediating phagocytosis, triggering inflammation, and targeting Ig to specific tissues. By using this protein, researchers can gain a deeper understanding of the immune system and develop new treatments for autoimmune diseases and other immune-related conditions.