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Recombinant EBOV GP-RBD Protein with Fc Tag

Our Recombinant EBOV GP-RBD Protein with Fc Tag is a cutting-edge research tool designed for in-depth studies on the Ebola virus. This protein is derived from the Sudan subtype, strain Gulu, and is expressed in HEK293 cells, ensuring high purity and consistency. The GP-RBD, or glycoprotein receptor-binding domain, is a critical component of the Ebola virus, playing a pivotal role in the virus's entry and attachment to host cells. The inclusion of the Fc tag enhances the protein's stability and facilitates its use in various applications.

Product Specifications and Features

This recombinant protein is produced with a calculated molecular weight of 59.0 kDa and an accession number of YP_138523.1. It is >95% pure as determined by reducing SDS-PAGE, ensuring reliable and reproducible results. The protein is endotoxin-free, with a level of <1.0 EU per μg, making it suitable for sensitive assays. The protein is lyophilized in a sterile PBS buffer, pH 7.4, with added protectants to maintain stability. Its formulation includes 5% - 8% trehalose, mannitol, and 0.01% Tween 80, providing optimal conditions for storage and reconstitution.

Applications and Benefits

The Recombinant EBOV GP-RBD Protein with Fc Tag is an invaluable tool for researchers studying the Ebola virus and its interaction with host cells. Its high purity, specificity, and stability make it ideal for various applications, including antibody production, vaccine development, and entry inhibitor research. This protein can also be used in diagnostic tests to detect Ebola virus infections. By understanding the molecular mechanisms of the Ebola virus, researchers can develop more effective treatments and preventive measures, ultimately saving lives.