Complete Recombinant Mouse Tim-3/havcr2 Protein (aa 20-193, His Tag) Get 35% Off Today [bMz4Ir28]

Complete Recombinant Mouse Tim-3/havcr2 Protein (aa 20-193, His Tag) Get 35% Off Today [bMz4Ir28]

Introducing our high-quality Complete Recombinant Mouse Tim-3/havcr2 Protein (aa 20-193, His Tag) Get 35% Off Today [bMz4Ir28], a crucial component for research into immune regulation and Th1-mediated immune responses. This protein, derived from HEK293 cells, offers a reliable source for your studies on TIM3, also known as HAVCR2, a transmembrane glycoprotein with significant implications in immune tolerance and anti-tumor immunity. With its specific sequence and molecular weight, this recombinant protein is ideal for various applications in immunology and oncology research.

Product Specifications and Properties

Our Recombinant Mouse TIM-3/HAVCR2 Protein is produced with exceptional purity, exceeding 95%, ensuring reliable and consistent results. It is expressed as a C-His tagged protein, which aids in purification and detection. The protein has a calculated molecular weight of 20.1 kDa and an observed molecular weight of 38-55 kDa, providing a clear indication of its identity and purity. This recombinant protein is not validated for activity, but its precise sequence and expression in HEK293 cells guarantee its effectiveness in various research applications.

Applications and Benefits

The Recombinant Mouse TIM-3/HAVCR2 Protein is a valuable tool for researchers studying immune regulation, particularly in the context of Th1-mediated immune responses and anti-tumor immunity. Its expression on Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells, makes it a key player in understanding immune tolerance and the balance between immune activation and suppression. This protein can be used to investigate the interaction between TIM3 and its ligand galectin-9, which is known to induce immunosuppressive functions. With its potential as a target molecule for immunotherapy, this recombinant protein offers a promising avenue for advancing our understanding of immune-related diseases and developing novel therapeutic strategies.