Clearance Recombinant Mouse Tyrosine-protein Kinase Receptor Ufo/axl Oncogene/ufo (c-6his) Buy Now [uKiXEWIQ]

Recombinant Mouse Tyrosine-protein Kinase UFO/AXL Oncogene/UFO

Our Recombinant Mouse Tyrosine-protein kinase UFO/AXL Oncogene/UFO (C-6His) is a highly purified protein, derived from HEK293 cells. This protein is a vital component in the TAM receptor tyrosine kinase family, known for its role in immune response regulation and cell survival. Its expression host, HEK293 cells, ensures a consistent and high-quality product. Key features include: Synonyms as Axl oncogene, Tyrosine-protein kinase receptor UFO, and UFO; species-specific mouse origin; and a sequence covering Ala19-Pro443. This recombinant protein is also tagged with C-His for enhanced detection and purification.

Product Specifications and Properties

This recombinant protein is highly pure, exceeding 95% purity as determined by reducing SDS-PAGE. It is free from endotoxins, with less than 1.0 EU per μg as confirmed by the LAL method. The calculated molecular weight is 47.2 kDa, with an observed molecular weight ranging from 60-80 kDa. The protein is lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, and is formulated with 5%-8% trehalose, mannitol, and 0.01% Tween 80 as protectants. Properties include: Storage stability up to 12 months at -20 to -80°C, 2-7 days at 4-8°C after reconstitution, and stability for 3 months at < -20°C upon aliquoting.

Practical Applications and Benefits

The Recombinant Mouse Tyrosine-protein kinase UFO/AXL Oncogene/UFO (C-6His) is an essential tool for researchers studying the TAM receptor tyrosine kinase family and its role in various biological processes, including immune response regulation, cell survival, and tumor progression. This protein is particularly valuable for investigating the potential of Axl as a novel therapeutic target in cancer. Applications include: Research into the mechanisms of immune regulation, cytokine secretion, and apoptosis; exploration of Axl's role in tumor cell invasiveness and metastasis; and development of targeted therapies for cancer. This recombinant protein is ideal for use in cell-based assays, immunoprecipitation, and Western blotting.