Classic Style Alox5 Polyclonal Antibody Store At -20°c - Almost Gone [xg9Z7NWT]

ALOX5 Polyclonal Antibody for Research Applications

Introducing our ALOX5 Polyclonal Antibody, a highly specialized tool designed for researchers seeking to study leukotriene synthesis and related inflammatory pathways. This antibody is a critical component for investigating the role of ALOX5, a key enzyme in the conversion of arachidonic acid to leukotrienes, which are significant mediators in numerous inflammatory and allergic conditions. Our ALOX5 Polyclonal Antibody is produced using rabbit immunoglobulins and offers robust reactivity across a range of species, including human, mouse, and rat. This versatile antibody is perfect for use in Immunohistochemistry (IHC) applications, enabling detailed examination of ALOX5 expression and localization within various tissues.

Product Specifications and Technical Details

Our ALOX5 Polyclonal Antibody is carefully formulated to ensure optimal performance and consistency. It is affinity-purified for maximum purity and contains 0.7 mg/mL concentration in a phosphate buffered solution with stabilizer and 50% glycerol to maintain stability. The antibody is unconjugated, allowing for flexibility in your experimental design. Key specifications include a purification method of affinity purification and a storage condition of -20°C, with a shelf life of 12 months when stored appropriately. The antibody is designed to detect the ALOX5 protein, which is known to shuttle between the cytoplasm and nucleus, and is localized in the nucleus upon phosphorylation at Ser-272, highlighting its dynamic cellular localization.

Applications and Target Audience

Ideal for researchers in the fields of cancer, cardiovascular disease, metabolism, and signal transduction, our ALOX5 Polyclonal Antibody is a valuable resource for understanding the complex biology of leukotriene synthesis. This antibody is particularly useful for exploring the impact of ALOX5 mutations, which may lead to reduced response to antileukotriene drugs, potentially affecting asthma treatment and contributing to conditions such as atherosclerosis and certain cancers. By utilizing our ALOX5 Polyclonal Antibody, scientists can gain deeper insights into these critical pathways, ultimately leading to advancements in therapeutic strategies and a better understanding of inflammatory diseases. Whether you are a seasoned researcher or just beginning in the field, this antibody is a reliable and indispensable tool for your studies.