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HMGB1 Polyclonal Antibody - Cold Storage Essential

The HMGB1 Polyclonal Antibody is a crucial tool for researchers specializing in cellular and molecular biology. This high-quality antibody is designed for use in various applications, including Western blotting (WB) and immunohistochemistry (IHC), making it a versatile choice for your laboratory needs. The antibody is raised against a synthetic peptide of human HMGB1, ensuring specificity and reliability.

• Reactivity with Human, Mouse, and Rat samples.
• Host species: Rabbit, providing a robust immune response.

With its ability to detect and analyze the High Mobility Group Box 1 protein, this antibody is invaluable for studying epigenetics, nuclear signaling, and cancer research. Its unconjugated form allows for flexibility in conjugation with other reagents for additional experiments.

Product Specifications and Storage Details

The HMGB1 Polyclonal Antibody is purified through affinity purification, ensuring a high level of purity and specificity. It is supplied in a phosphate buffered solution containing 0.05% stabilizer and 50% glycerol, which preserves the antibody's stability and longevity. The antibody is concentrated at 0.3 mg/mL, providing a convenient concentration for various experimental setups.

• Storage at -20°C maintains stability for up to 12 months.
• Prevent freeze/thaw cycles to maintain antibody integrity.

The antibody's calculated molecular weight is 25 kDa, and it is primarily localized in the nucleus, cytoplasm, and secreted into the extracellular environment, making it a dynamic marker for cellular processes.

Applications and Benefits

This HMGB1 Polyclonal Antibody is ideal for researchers seeking to explore the complex roles of HMGB1 in cellular signaling and disease mechanisms. Its applications in cancer research, particularly in the study of epigenetics and nuclear signaling, are significant. The antibody's broad reactivity with multiple species and its versatility in various experimental techniques make it an indispensable tool in the laboratory.

• Enhance your research capabilities with a reliable antibody for HMGB1 detection.
• Conduct advanced experiments in Western blotting and immunohistochemistry.

Whether you are a seasoned researcher or just starting out, the HMGB1 Polyclonal Antibody is a valuable addition to your toolkit.