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PRKDC Polyclonal Antibody: A Powerful Tool for DNA Damage Research

The PRKDC Polyclonal Antibody is a vital research tool for scientists studying DNA damage and repair mechanisms. This high-quality antibody is specifically designed to recognize and bind to the PRKDC protein, also known as DNA-PKcs, a crucial serine/threonine-protein kinase involved in DNA nonhomologous end joining (NHEJ) and V(D)J recombination. With its ability to detect and quantify PRKDC expression, this antibody is an essential component for investigating the role of DNA-PKcs in various cellular processes, including DNA repair, transcription modulation, and chromosomal stability.

Key Features and Specifications

This PRKDC Polyclonal Antibody is produced in rabbits and offers a robust reactivity against human and mouse PRKDC proteins. It is available in a convenient 1 mg/mL concentration and is stored at -20°C for long-term stability. The antibody is purified using affinity purification techniques to ensure high purity and specificity. Key features include:

• Host: Rabbit
• Reactivity: Human, Mouse
• Applications: WB, IHC-p, IF
• Clonality: Polyclonal
• Immunogen: Synthesized peptide derived from the C-terminal region of human DNA-PKCS

Applications and Benefits

The PRKDC Polyclonal Antibody is versatile and can be used in various experimental techniques, including Western blotting (WB), immunohistochemistry (IHC-p), and immunofluorescence (IF). This antibody is ideal for researchers investigating DNA damage response mechanisms, cancer biology, and epigenetics. Its high specificity and sensitivity make it a valuable tool for detecting and quantifying PRKDC expression in various cell types and tissues. By using this antibody, researchers can gain valuable insights into the complex processes of DNA repair and cellular response to DNA damage.