Last Chance Recombinant Human Ret Kinase Protein (his Tag) Series [9h2IyHpe]

Last Chance Recombinant Human Ret Kinase Protein (his Tag) Series [9h2IyHpe]

The Last Chance Recombinant Human Ret Kinase Protein (his Tag) Series [9h2IyHpe] is a high-quality recombinant protein designed for various research applications. This protein is produced in HEK293 cells and contains a His Tag for easy purification. With a purity of >92% as determined by reducing SDS-PAGE, this protein is ideal for use in biochemical studies, cell-based assays, and protein engineering.

Product Properties and Specifications

This recombinant protein is expressed with a sequence covering Met 1-Arg 635 and has a calculated molecular weight of 69.1 kDa. The observed molecular weight is approximately 110-120 kDa, indicating its proper folding and stability. The protein is tagged with an N-His tag, making it easy to purify using immobilized metal affinity chromatography (IMAC). It is important to note that the bio-activity of this protein has not been validated.

Practical Uses and Benefits

The Last Chance Recombinant Human Ret Kinase Protein (his Tag) Series [9h2IyHpe] is a valuable tool for researchers studying the RET proto-oncogene, which is involved in various cellular processes, including cell proliferation, neuronal navigation, cell migration, and cell differentiation. This protein can be used to study the effects of RET on PTK2/FAK1 phosphorylation, cell death/survival balance, and positional information. Its involvement in the development of enteric nervous system and renal organogenesis during embryonic life makes it a crucial component for understanding neuroendocrine cancers and related diseases. The protein's purity, stability, and ease of use make it a versatile tool for a wide range of research applications.