Top Pick Recombinant Human C-kit/cd117 Protein (his Tag)(active) Up To 65% Off [3m5AN8ca]

Top Pick Recombinant Human C-kit/cd117 Protein (his Tag)(active) Up To 65% Off [3m5AN8ca]

The Top Pick Recombinant Human C-kit/cd117 Protein (his Tag)(active) Up To 65% Off [3m5AN8ca] is a high-quality, active protein designed for various research applications. This protein is produced in HEK293 cells and offers a reliable source for studies involving the c-KIT/CD117 receptor. With a purity of over 97% and a calculated molecular weight of 56.7 kDa, this protein is ideal for use in immunoassays, cell culture, and other biological research. Here are some key features that make this product stand out:

• Expression Host: HEK293 Cells
• Sequence: Met 1-Thr 516
• Accession: P10721-2

Product Properties and Specifications

The Top Pick Recombinant Human C-kit/cd117 Protein (his Tag)(active) Up To 65% Off [3m5AN8ca] is carefully processed to ensure optimal performance and stability. It is endotoxin-free, with a level below 1.0 EU per μg, making it suitable for sensitive assays. The protein is lyophilized from sterile PBS buffer, pH 7.4, and typically contains 5% - 8% trehalose, mannitol, and 0.01% Tween 80 as protectants. This formulation ensures the protein's integrity and facilitates easy reconstitution. Here are some important specifications:

• Purity: > 97% as determined by reducing SDS-PAGE
• Endotoxin: < 1.0 EU per μg
• Storage: -20 to -80℃ for up to 12 months, 4-8℃ for 2-7 days after reconstitution

Practical Applications and Benefits

The Top Pick Recombinant Human C-kit/cd117 Protein (his Tag)(active) Up To 65% Off [3m5AN8ca] is a versatile tool for researchers studying c-KIT/CD117 signaling pathways and related diseases. Its high bio-activity allows for efficient binding to biotinylated human KITL with an EC50 of 2.0-9.0 ng/ml. This protein is widely used in the diagnosis of gastrointestinal stromal tumors (GISTs), mast cell tumors, and distinguishing between seminomas and embryonal carcinomas. It is also valuable for exploring the role of c-Kit in acute myelogenous leukemia (AML) and other related conditions. By using this product, researchers can gain deeper insights into these complex diseases and advance their research efforts:

• Diagnosis of GISTs and mast cell tumors
• Understanding c-Kit signaling in AML and other diseases
• Development of targeted therapies for various cancers and blood disorders