Final Markdown Recombinant Human Smac/diablo Protein (his Tag)(active) + Gift Included [YO1G8JQ5]

Final Markdown Recombinant Human Smac/diablo Protein (his Tag)(active) + Gift Included [YO1G8JQ5]

Discover the power of recombinant human SMAC/Diablo protein, a vital component in understanding apoptosis and its role in various cellular processes. This active protein, expressed in E. coli and tagged with His, is a crucial tool for researchers investigating cell death and signaling pathways. Its purity exceeds 90%, ensuring reliable and consistent results in your experiments.

Product Specifications and Properties

The recombinant human SMAC/Diablo protein is a recombinant protein with a sequence spanning from Ala 56 to Asp 239. It carries a calculated molecular weight of 22 kDa and an observed molecular weight of 22 kDa. This protein is active and can bind recombinant human XIAP-AVI with a linear range of 0.125-1.0 μg/ml, making it ideal for in vitro studies. Key properties include a purity of >90% as determined by reducing SDS-PAGE, and it is lyophilized from sterile PBS, pH 7.4, with additives like trehalose, mannitol, and Tween 80 for stability and protection.

Applications and Benefits

The recombinant human SMAC/Diablo protein is a valuable asset for researchers studying apoptosis, cancer, and other cellular processes. Its ability to interact with IAPs and promote apoptosis makes it a key player in understanding the mechanisms of programmed cell death. This protein is suitable for various applications, including cell-based assays, immunoprecipitation, and as a research tool for understanding the role of Smac/Diablo in various diseases, such as colorectal cancer. By using this high-quality protein, you can enhance your research capabilities and contribute to the advancement of medical science.