Compact Recombinant Human Interleukin-17f/il-17f Protein (his Tag)(active) Buy Now [T2tdcA7M]

Compact Recombinant Human Interleukin-17f/il-17f Protein (his Tag)(active) Buy Now [T2tdcA7M]

The Compact Recombinant Human Interleukin-17f/il-17f Protein (his Tag)(active) Buy Now [T2tdcA7M] is a high-quality, active protein derived from HEK293 cells. This protein, also known as Cytokine ML, IL17F, CANDF, and IL-24, is a potent activator of immune responses and has a wide range of applications in research and diagnostics. Its active nature and high purity (>95%) make it an ideal tool for studying the role of interleukin-17F in various biological processes.

Product Specifications and Properties

This recombinant protein is expressed with a C-His tag and has a calculated molecular weight of 16.0 kDa, observed as 19 kDa. It is produced in HEK293 cells and has a sequence from Arg31 to Gln163. The protein is bioactive, with an ED₅₀ of 47.94 ng/ml when immobilized with Mouse IL-17RA-Fc. The product is >95% pure as determined by reducing SDS-PAGE and has an endotoxin level of < 1.0 EU per μg. The protein is lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4, with protectants like trehalose, mannitol, and Tween 80 added before lyophilization.

Applications and Benefits

The Recombinant Human Interleukin-17F/IL-17F Protein is a valuable tool for researchers studying immune responses, inflammation, and cartilage matrix turnover. Its ability to stimulate cytokine production, regulate T-cell proliferation, and inhibit angiogenesis makes it particularly useful in exploring the role of interleukin-17F in various diseases, including familial candidiasis type 6 (CANDF6). This protein is suitable for use in ELISA, Western blot, immunoprecipitation, and other immunoassays, providing researchers with a reliable and efficient reagent for their experiments. With its high purity, bioactivity, and ease of use, this recombinant protein is an essential addition to any laboratory working on interleukin-17F research.