Viral Recombinant Human Interleukin-4/il-4 Protein (active) Tool [LgrSey1H]

High-Quality Recombinant Human Interleukin-4 (IL-4)

Welcome to our premium Recombinant Human Interleukin-4 (IL-4) protein, a vital component for various biological research applications. This active protein, sourced from E.coli, is produced through a state-of-the-art recombinant technology, ensuring high purity and reliability. With its >98% purity as determined by reducing SDS-PAGE and minimal endotoxin levels, our IL-4 protein is suitable for a wide range of experiments and assays.

• High Purity: Our IL-4 protein boasts a purity level exceeding 98%, guaranteeing consistent and reproducible results in your experiments.
• Minimal Endotoxin Levels: Endotoxin levels are kept below 0.1 EU per μg, ensuring the integrity of your research findings.

Key Features and Specifications

Our Recombinant Human IL-4 protein offers several key features and specifications that make it an ideal choice for your research needs. It is expressed as a C-His-tagged protein with a calculated molecular weight of 15.9 kDa and an observed molecular weight of 12 kDa. The protein sequence spans from His25 to Ser153, and it is produced with a specific activity of >2.8 x 10⁷ IU/mg.

• Expression Host: E.coli
• Sequence: His25-Ser153
• Calculated Molecular Weight: 15.9 kDa
• Observed Molecular Weight: 12 kDa
• Specific Activity: >2.8 x 10⁷ IU/mg

Practical Applications and Benefits

The Recombinant Human IL-4 protein has a wide range of practical applications in research, including the induction of TF-1 cells proliferation, regulation of T and B cell responses, and immunoglobulin class switching. By offering a reliable and high-quality source of IL-4, our product helps researchers achieve consistent and reproducible results.

• Induces TF-1 Cells Proliferation: The protein demonstrates a strong bio-activity, with an ED₅₀ for this effect less than 0.2 ng/mL.
• Regulates T and B Cell Responses: IL-4 plays a critical role in the differentiation of naive CD4+ T cells into helper Th2 cells, promoting humoral immune responses.
• Immunoglobulin Class Switching: IL-4 is essential for the regulation of immunoglobulin class switching to IgG1 and IgE isotypes, which are crucial for allergic responses.