Complete Recombinant Human Pd-1/pdcd1 Protein (mfc Tag)(active) Perfect For Gifting [UThG8C1S]

Recombinant Human PD-1 Protein (mFc Tag)(Active)

The Complete Recombinant Human Pd-1/pdcd1 Protein (mfc Tag)(active) Perfect For Gifting [UThG8C1S] is a highly purified, recombinant protein that offers a powerful tool for research into immune regulation and cell signaling. This active protein is expressed in HEK293 cells and is tagged with the murine Fc (mFc) domain, providing enhanced stability and ease of use in various experimental applications. Key features include: a calculated molecular weight of 42.0 kDa, observed molecular weight of 60 kDa, and bio-activity demonstrated by its ability to bind Human PD-1-mFc with an ED50 of 12.53 ng/ml.

• High purity: > 95% as determined by reducing SDS-PAGE.
• Low endotoxin: < 1.0 EU per μg of the protein.

Product Specifications and Technical Details

This recombinant protein is produced using a proprietary expression system, ensuring consistent quality and reliability. The protein is lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, and typically contains 5% - 8% trehalose, mannitol, and 0.01% Tween 80 as protectants. The protein is stored at -20 to -80℃ for long-term stability and can be reconstituted with the buffer provided in the manual. Technical specifications include:

• Expression Host: HEK293 Cells
• Sequence: Pro21-Gln167
• Accession Number: Q15116

Applications and Benefits

The Recombinant Human PD-1 Protein is an invaluable resource for researchers studying the role of PD-1 in immune regulation, autoimmune diseases, and cancer immunotherapy. Its high purity, low endotoxin levels, and specific bio-activity make it ideal for a wide range of applications, including in vitro binding assays, ELISA, and immunoprecipitation. Key benefits include:

• Enhanced Stability: The mFc tag improves the protein's stability and shelf life.
• High Bio-activity: Demonstrated by its ability to bind Human PD-1-mFc with high affinity.

This product is suitable for researchers in academia, biotech, and pharmaceutical industries who are focused on understanding the complex mechanisms of immune response and developing new therapeutic strategies.