Fast Shipping Recombinant Human Cd86/b7-2 Protein (val185ile, His Tag)(active) Now 80% Cheaper [wcZjQheA]

Fast Shipping Recombinant Human Cd86/b7-2 Protein (val185ile, His Tag)(active) Now 80% Cheaper [wcZjQheA]

Introducing our high-quality Recombinant Human CD86/B7-2 Protein, a crucial component for research and development in immunology and cell biology. This active protein, with a Val185Ile mutation and His Tag, is a powerful tool for understanding T-cell activation and costimulation. Its recombinant nature ensures purity and consistency, making it ideal for various applications in the laboratory.

Product Properties and Specifications

Our Recombinant Human CD86/B7-2 Protein is produced in HEK293 cells, offering a reliable source for your research needs. It has a calculated molecular weight of 26.7 kDa and an observed molecular weight of 57-66 kDa, demonstrating its stability and integrity. The protein is >95% pure, as determined by reducing SDS-PAGE, and contains minimal endotoxin levels, ensuring reliable results in your experiments. Key features include:

• Expression Host: HEK293 Cells
• Sequence: Ala24-Pro247
• Accession: AAH40261.1
• Tag: C-His
• Bio-activity: Bound to Mouse CTLA-4-Fc with an affinity constant of 5.65 nM

Practical Applications and Benefits

This Recombinant Human CD86/B7-2 Protein is an essential tool for researchers studying T-cell activation, costimulation, and immune responses. Its ability to bind CD28 or CTLA-4 makes it ideal for investigating the early events of T-cell activation and the decision-making process between immunity and anergy. With its high purity, minimal endotoxin levels, and active status, this protein is perfect for use in various applications, including:

• Immunology Research: Investigating T-cell activation and costimulation pathways
• Cell Biology Studies: Understanding the role of CD86/B7-2 in T-cell signaling
• Therapeutic Development: Exploring potential treatments for immune-related diseases